Journal: NeuroImage : Clinical

Article Title: Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

doi: 10.1016/j.nicl.2015.11.019

Figure Lengend Snippet: Summary of ROI-based quantitative DTI studies.

Article Snippet: ; prospective, cross-sectional , MS (96 total, 52 RRMS, 33 SPMS, 11 PPMS) vs. HCs (21) , 1.5 T; Siemens; tailored cervical PAC , • C1–C7 • Slice orientation, number, gap NR , • 2D GE ± MT pre-pulse (Gaussian, 1.5 kHz offset, 7.7 ms, 500°), FA = 20°, NEX = 2 , 192 × 250 mm 2 ; 256 × 256; 1 × 1 × 5 mm 3 ; 640/12; no; NR , MTR, histogram peak, location , Semi-automatic, whole-cord, excluding voxels with MTR < 10% , • EDSS , • Decreased MTR in MS patients: 44% vs. 46% P = 0.006 • Peak location and height were independent predictors of EDSS ≥ 4.0 in multivariate analysis , High; correlation coefficient not calculated.

Techniques: Diagnostic Assay, Sequencing, Significance Assay, Sampling, Biomarker Discovery, Comparison, Selection

Journal: NeuroImage : Clinical

Article Title: Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

doi: 10.1016/j.nicl.2015.11.019

Figure Lengend Snippet: Summary of MT studies.

Article Snippet: ; prospective, cross-sectional , MS (96 total, 52 RRMS, 33 SPMS, 11 PPMS) vs. HCs (21) , 1.5 T; Siemens; tailored cervical PAC , • C1–C7 • Slice orientation, number, gap NR , • 2D GE ± MT pre-pulse (Gaussian, 1.5 kHz offset, 7.7 ms, 500°), FA = 20°, NEX = 2 , 192 × 250 mm 2 ; 256 × 256; 1 × 1 × 5 mm 3 ; 640/12; no; NR , MTR, histogram peak, location , Semi-automatic, whole-cord, excluding voxels with MTR < 10% , • EDSS , • Decreased MTR in MS patients: 44% vs. 46% P = 0.006 • Peak location and height were independent predictors of EDSS ≥ 4.0 in multivariate analysis , High; correlation coefficient not calculated.

Techniques: Diagnostic Assay, Activation Assay, Isolation

Journal: NeuroImage : Clinical

Article Title: Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

doi: 10.1016/j.nicl.2015.11.019

Figure Lengend Snippet: Summary of MRS studies.

Article Snippet: ; prospective, cross-sectional , MS (96 total, 52 RRMS, 33 SPMS, 11 PPMS) vs. HCs (21) , 1.5 T; Siemens; tailored cervical PAC , • C1–C7 • Slice orientation, number, gap NR , • 2D GE ± MT pre-pulse (Gaussian, 1.5 kHz offset, 7.7 ms, 500°), FA = 20°, NEX = 2 , 192 × 250 mm 2 ; 256 × 256; 1 × 1 × 5 mm 3 ; 640/12; no; NR , MTR, histogram peak, location , Semi-automatic, whole-cord, excluding voxels with MTR < 10% , • EDSS , • Decreased MTR in MS patients: 44% vs. 46% P = 0.006 • Peak location and height were independent predictors of EDSS ≥ 4.0 in multivariate analysis , High; correlation coefficient not calculated.

Techniques: Diagnostic Assay

Journal: NeuroImage : Clinical

Article Title: Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

doi: 10.1016/j.nicl.2015.11.019

Figure Lengend Snippet: Summary of fMRI studies.

Article Snippet: ; prospective, cross-sectional , MS (96 total, 52 RRMS, 33 SPMS, 11 PPMS) vs. HCs (21) , 1.5 T; Siemens; tailored cervical PAC , • C1–C7 • Slice orientation, number, gap NR , • 2D GE ± MT pre-pulse (Gaussian, 1.5 kHz offset, 7.7 ms, 500°), FA = 20°, NEX = 2 , 192 × 250 mm 2 ; 256 × 256; 1 × 1 × 5 mm 3 ; 640/12; no; NR , MTR, histogram peak, location , Semi-automatic, whole-cord, excluding voxels with MTR < 10% , • EDSS , • Decreased MTR in MS patients: 44% vs. 46% P = 0.006 • Peak location and height were independent predictors of EDSS ≥ 4.0 in multivariate analysis , High; correlation coefficient not calculated.

Techniques: Blocking Assay, Activation Assay